Dosage
Trials use 100 g to 500 g of fresh cladode per day, or smaller doses of standardised extract. The OpunDia product has been studied at 500 mg before meals. Ask your healthcare provider before use if you take blood sugar medicine.
Ingredient guide
Prickly pear cactus pads (nopal) show modest blood sugar reductions in small trials, while the fruit shows little effect. A systematic review supports cladode use as a functional food but concludes evidence is too limited for routine use in diabetes care.
Limited evidencePrickly pear is a cactus in the Opuntia genus, native to Mexico and the American southwest. Both the flat green pads (called cladodes or nopal) and the magenta fruits are eaten. The cladodes are rich in soluble fibre, while the fruits are sweet and full of vitamin C.
A systematic review concluded that the cladode shows promise in reducing serum glucose and insulin, with prickly pear products demonstrating significant reductions in some trials. The fruit, in contrast, was predominately reported to have no significant effects on glucose or insulin. The reviewer noted that overall evidence is insufficient to recommend Opuntia fruit products as an alternative or complementary therapy for type 2 diabetes. We grade the evidence as limited.
Trials use 100 g to 500 g of fresh cladode per day, or smaller doses of standardised extract. The OpunDia product has been studied at 500 mg before meals. Ask your healthcare provider before use if you take blood sugar medicine.
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Nopal is the Spanish name for the flat green cactus pads of prickly pear, eaten as a vegetable across Mexico.